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A cryptic subgroup of Anopheles gambiae is highly susceptible to human malaria parasites.
- Source :
-
Science (New York, N.Y.) [Science] 2011 Feb 04; Vol. 331 (6017), pp. 596-8. - Publication Year :
- 2011
-
Abstract
- Population subgroups of the African malaria vector Anopheles gambiae have not been comprehensively characterized owing to the lack of unbiased sampling methods. In the arid savanna zone of West Africa, where potential oviposition sites are scarce, widespread collection from larval pools in the peridomestic human habitat yielded a comprehensive genetic survey of local A. gambiae population subgroups, independent of adult resting behavior and ecological preference. A previously unknown subgroup of exophilic A. gambiae is sympatric with the known endophilic A. gambiae in this region. The exophilic subgroup is abundant, lacks differentiation into M and S molecular forms, and is highly susceptible to infection with wild Plasmodium falciparum. These findings might have implications for the epidemiology of malaria transmission and control.
- Subjects :
- Animals
Anopheles classification
Anopheles physiology
Bayes Theorem
Burkina Faso epidemiology
Genotype
Host-Parasite Interactions
Housing
Humans
Hybridization, Genetic
Insect Vectors physiology
Larva genetics
Larva parasitology
Larva physiology
Malaria, Falciparum epidemiology
Malaria, Falciparum prevention & control
Malaria, Falciparum transmission
Microsatellite Repeats
Mosquito Control
Polymorphism, Single Nucleotide
Population Dynamics
Anopheles genetics
Anopheles parasitology
Insect Vectors genetics
Insect Vectors parasitology
Plasmodium falciparum physiology
Subjects
Details
- Language :
- English
- ISSN :
- 1095-9203
- Volume :
- 331
- Issue :
- 6017
- Database :
- MEDLINE
- Journal :
- Science (New York, N.Y.)
- Publication Type :
- Academic Journal
- Accession number :
- 21292978
- Full Text :
- https://doi.org/10.1126/science.1196759