Back to Search Start Over

[Synaptic localization of 5'-nucleotidase activity in the cerebellar cortex in adult rats irradiated by X rays after birth].

Authors :
Bailly Y
Schoen SW
Delhaye-Bouchaud N
Kreutzberg GW
Mariani J
Source :
Comptes rendus de l'Academie des sciences. Serie III, Sciences de la vie [C R Acad Sci III] 1990; Vol. 311 (13), pp. 487-93.
Publication Year :
1990

Abstract

5'-nucleotidase cytochemistry was performed in the cerebellum of adult rats exposed previously to a single postnatal X-irradiation which maintains until adulthood the normally transient multiple innervation of cerebellar Purkinje cells by climbing fibers. 5'-nucleotidase activity persists in climbing fiber synapses and other asymmetrical synapses while it is transient during normal development. Therefore, in the X-irradiated rat, an immature stage of the excitatory synapses persists which, for the climbing fibers, coïncides with or precedes their involution during normal development.

Details

Language :
French
ISSN :
0764-4469
Volume :
311
Issue :
13
Database :
MEDLINE
Journal :
Comptes rendus de l'Academie des sciences. Serie III, Sciences de la vie
Publication Type :
Academic Journal
Accession number :
2129114