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Molecular and phenotypic characterization of Phialemonium and Lecythophora isolates from clinical samples.
- Source :
-
Journal of clinical microbiology [J Clin Microbiol] 2011 Apr; Vol. 49 (4), pp. 1209-16. Date of Electronic Publication: 2011 Jan 26. - Publication Year :
- 2011
-
Abstract
- Several members of the fungal genera Phialemonium and Lecythophora are occasional agents of severe human and animal infections. These species are difficult to identify, and relatively little is known about their frequency in the clinical setting. The objective of this study was to characterize morphologically and molecularly, on the basis of the analysis of large-subunit ribosomal DNA sequences, a set of 68 clinical isolates presumed to belong to these genera. A total of 59 isolates were determined to be Phialemonium species (n = 32) or a related Cephalotheca species (n = 6) or Lecythophora species (n = 20) or a related Coniochaeta species (n = 1). Nine isolates identified to be Acremonium spp. or Phaeoacremonium spp. were excluded from further study. The most common species were Phialemonium obovatum and Phialemonium curvatum, followed by Lecythophora hoffmannii, Cephalotheca foveolata, and Lecythophora mutabilis.
- Subjects :
- Antifungal Agents pharmacology
Ascomycota drug effects
Ascomycota genetics
DNA, Fungal chemistry
DNA, Fungal genetics
DNA, Ribosomal chemistry
DNA, Ribosomal genetics
Genes, rRNA
Humans
Microbial Sensitivity Tests
Microscopy
RNA, Fungal genetics
RNA, Ribosomal, 28S genetics
Sequence Analysis, DNA
Ascomycota classification
Ascomycota isolation & purification
Mycoses microbiology
Subjects
Details
- Language :
- English
- ISSN :
- 1098-660X
- Volume :
- 49
- Issue :
- 4
- Database :
- MEDLINE
- Journal :
- Journal of clinical microbiology
- Publication Type :
- Academic Journal
- Accession number :
- 21270235
- Full Text :
- https://doi.org/10.1128/JCM.01979-10