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Improvement in sexual functioning in patients with type 2 diabetes and depression treated with bupropion.
- Source :
-
Diabetes care [Diabetes Care] 2011 Feb; Vol. 34 (2), pp. 332-4. - Publication Year :
- 2011
-
Abstract
- Objective: Major depressive disorder (MDD) and type 2 diabetes have independent adverse effects on sexual functioning (SF). Bupropion (BU) reportedly has few sexual side effects, but its use in diabetes has not been studied.<br />Research Design and Methods: This article reports a planned secondary analysis of SF in 90 patients with type 2 diabetes treated with BU for MDD.<br />Results: At baseline, 71.1% of patients had insufficient SF. Mean Sexual Energy Scale (SES) scores improved during treatment (P < 0.0001), as did the percentage with sufficient SF (30.6 vs. 68.1%, P = 0.001). Patients with persistent hyperglycemia had higher rates of sexual dysfunction; however, SES improvement was evident in some with persistent depression or hyperglycemia (18.2% and 25.9%, respectively).<br />Conclusions: Insufficient SF is prevalent and may be suspected in patients with MDD and type 2 diabetes. BU treatment of MDD had few sexual side effects and was associated with significant improvements in SF.
- Subjects :
- Adolescent
Adult
Aged
Aged, 80 and over
Antidepressive Agents, Second-Generation administration & dosage
Antidepressive Agents, Second-Generation adverse effects
Bupropion adverse effects
Depressive Disorder, Major epidemiology
Diabetes Mellitus, Type 2 epidemiology
Female
Humans
Hyperglycemia epidemiology
Hyperglycemia psychology
Male
Middle Aged
Prevalence
Risk Factors
Sexual Dysfunctions, Psychological epidemiology
Young Adult
Bupropion administration & dosage
Depressive Disorder, Major drug therapy
Diabetes Mellitus, Type 2 psychology
Sexual Behavior drug effects
Sexual Dysfunctions, Psychological drug therapy
Subjects
Details
- Language :
- English
- ISSN :
- 1935-5548
- Volume :
- 34
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- Diabetes care
- Publication Type :
- Academic Journal
- Accession number :
- 21270190
- Full Text :
- https://doi.org/10.2337/dc10-1714