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In vivo expression of an aberrant MYB-GATA1 fusion induces leukemia in the presence of GATA1 reduced levels.
- Source :
-
Leukemia [Leukemia] 2011 Apr; Vol. 25 (4), pp. 733-6. Date of Electronic Publication: 2011 Jan 21. - Publication Year :
- 2011
- Subjects :
- Animals
GATA1 Transcription Factor metabolism
Gene Rearrangement
Leukemia, Experimental pathology
Lymphoma etiology
Lymphoma pathology
Mice
Mice, Knockout
Proto-Oncogene Proteins c-myb metabolism
Thymus Neoplasms etiology
Thymus Neoplasms pathology
Tumor Suppressor Protein p53 physiology
Cell Transformation, Neoplastic
GATA1 Transcription Factor genetics
Leukemia, Experimental etiology
Oncogene Proteins, Fusion genetics
Proto-Oncogene Proteins c-myb genetics
Subjects
Details
- Language :
- English
- ISSN :
- 1476-5551
- Volume :
- 25
- Issue :
- 4
- Database :
- MEDLINE
- Journal :
- Leukemia
- Publication Type :
- Report
- Accession number :
- 21252985
- Full Text :
- https://doi.org/10.1038/leu.2010.317