Evaluation of mutations in the isocitrate dehydrogenase genes in therapy-related and secondary acute myeloid leukaemia identifies a patient with clonal evolution to IDH2 R172K homozygosity due to uniparental disomy.

Authors :: Pichler MM
Bodner C
Fischer C
Deutsch AJ
Hiden K
Beham-Schmid C
Linkesch W
Guelly C
Sill H
Wölfler A
Source :: British journal of haematology [Br J Haematol] 2011 Mar; Vol. 152 (5), pp. 669-72. Date of Electronic Publication: 2011 Jan 20.
Publication Year :: 2011

Subjects :: Adolescent
Adult
Aged
Aged, 80 and over
Female
Humans
Male
Middle Aged
Young Adult
Isocitrate Dehydrogenase genetics
Leukemia, Myeloid, Acute genetics
Mutation
Neoplasms, Second Primary genetics
Uniparental Disomy

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