Oral and maxillofacial desmoid-type fibromatoses in an eastern Chinese population: a report of 20 cases.

Authors :: Min R
Zun Z
Lizheng W
Minjun D
Shengwen L
Wenjun Y
Chenping Z
Source :: Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics [Oral Surg Oral Med Oral Pathol Oral Radiol Endod] 2011 Mar; Vol. 111 (3), pp. 340-5. Date of Electronic Publication: 2011 Jan 17.
Publication Year :: 2011
Abstract: Objective: Primary desmoid-type fibromatoses arising from the oral and maxillofacial region are uncommon and hold the character of local invasion and regional recurrence. The purpose of this study was to analyze the clinicoepidemiologic characteristics of this rare disease in an eastern Chinese population.<br />Study Design: Epidemiological and clinicopathological data on 20 patients were reviewed from the hospital records and analyzed accordingly.<br />Results: Twelve males and 8 females with a ratio of 3:2 were involved. The mandible was the most common site of presentation. Suspected malignant change was found in 6 cases and an extremely high recurrence rate was also found in up to 53%. Abnormally high blood levels of alkaline phosphatase were found in 65% of patients, which had a close relation with tumor malignant change.<br />Conclusion: Chinese people are more susceptible to desmoid-type fibromatoses and are at an extremely high risk of regional malignant change. Elevated serum alkaline phosphatase levels may be taken as an indicator for malignant transformation.<br /> (Copyright © 2011 Mosby, Inc. All rights reserved.)

Language :: English
ISSN :: 1528-395X
Volume :: 111
Issue :: 3
Database :: MEDLINE
Journal :: Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics
Publication Type :: Academic Journal
Accession number :: 21247785
Full Text :: https://doi.org/10.1016/j.tripleo.2010.10.019

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