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Effects of meals with different glycaemic index on postprandial blood glucose response in patients with Type 1 diabetes treated with continuous subcutaneous insulin infusion.
- Source :
-
Diabetic medicine : a journal of the British Diabetic Association [Diabet Med] 2011 Feb; Vol. 28 (2), pp. 227-9. - Publication Year :
- 2011
-
Abstract
- Objective: To evaluate the impact of high-glycaemic index and low-glycaemic index meals on postprandial blood glucose in patients with Type 1 diabetes treated with continuous subcutaneous insulin infusion.<br />Methods: Sixteen patients with Type 1 diabetes under continuous subcutaneous insulin infusion treatment, age 36±0.5 years (mean±sem), HbA(1c) 7.6±0.2% (56±1.1 mmol/mol), consumed two test meals with an identical macronutrient composition, but with a different glycaemic index: 59 vs. 90. Blood glucose was checked before the test meal and every 30 min thereafter for 180 min. The same preprandial insulin dose was administered on the two occasions.<br />Results: Blood glucose concentrations following the low-glycaemic index meal were significantly lower than those of the high-glycaemic index meal (P<0.05 to P<0.01). The blood glucose area under the curve after the low-glycaemic index meal was 20% lower than after the high-glycaemic meal (P=0.006).<br />Conclusions: Our data show that meals with the same carbohydrate content but a different glycaemic index produce clinically significant differences in postprandial blood glucose.<br /> (© 2011 The Authors. Diabetic Medicine © 2011 Diabetes UK.)
- Subjects :
- Adult
Diabetes Mellitus, Type 1 diet therapy
Diabetes Mellitus, Type 1 drug therapy
Female
Humans
Insulin Infusion Systems
Male
Postprandial Period
Treatment Outcome
Blood Glucose metabolism
Diabetes Mellitus, Type 1 metabolism
Dietary Carbohydrates metabolism
Dietary Fiber metabolism
Hypoglycemic Agents administration & dosage
Insulin administration & dosage
Subjects
Details
- Language :
- English
- ISSN :
- 1464-5491
- Volume :
- 28
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- Diabetic medicine : a journal of the British Diabetic Association
- Publication Type :
- Academic Journal
- Accession number :
- 21219435
- Full Text :
- https://doi.org/10.1111/j.1464-5491.2010.03176.x