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[The effect of renal ischemic preconditioning on the myocardial ischemic/reperfusion injury in rabbits].
- Source :
-
Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology [Zhongguo Ying Yong Sheng Li Xue Za Zhi] 2001 Nov; Vol. 17 (4), pp. 366-9. - Publication Year :
- 2001
-
Abstract
- Aim: To investigate whether renal ischemic preconditioning could protect myocardium from ischemic-reperfusion injury.<br />Methods: Thirty-two adult white rabbits were randomly divided into four groups: group sham operation (SO), myocardial ischemic-reperfusion (I/R), classical ischemic preconditioning (CIPC) and renal ischemic preconditioning (RIPC). Changes of left ventricular functions, myocardial infarct size, myocardial ultrastructure and cardiac arrhythmia were observed.<br />Results: RIPC and CIPC could reduce the myocardial infarct size and the attack rate of arrhythmia (P < 0.01 vs I/R); improve the left ventricular functions (P < 0.01 vs I/R) and minimized the ultrastructure injury of I/R myocardium.<br />Conclusion: The RIPC might elicit a myocardial protection against ischemic-reperfusion injury, which is similar to the effect of CIPC.
Details
- Language :
- Chinese
- ISSN :
- 1000-6834
- Volume :
- 17
- Issue :
- 4
- Database :
- MEDLINE
- Journal :
- Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology
- Publication Type :
- Academic Journal
- Accession number :
- 21207703