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Prostatic arterial embolization to treat benign prostatic hyperplasia.
- Source :
-
Journal of vascular and interventional radiology : JVIR [J Vasc Interv Radiol] 2011 Jan; Vol. 22 (1), pp. 11-9; quiz 20. - Publication Year :
- 2011
-
Abstract
- Purpose: To evaluate whether prostatic arterial embolization (PAE) might be a feasible procedure to treat lower urinary tract symptoms associated with benign prostatic hyperplasia (BPH).<br />Materials and Methods: Fifteen patients (age range, 62-82 years; mean age, 74.1 y) with symptomatic BPH after failure of medical treatment were selected for PAE with nonspherical 200-μm polyvinyl alcohol particles. The procedure was performed by a single femoral approach. Technical success was considered when selective prostatic arterial catheterization and embolization was achieved on at least one pelvic side.<br />Results: PAE was technically successful in 14 of the 15 patients (93.3%). There was a mean follow-up of 7.9 months (range, 3-12 months). International Prostate Symptom Score decreased a mean of 6.5 points (P = .005), quality of life improved 1.14 points (P = .065), International Index of Erectile Function increased 1.7 points (P = .063), and peak urinary flow increased 3.85 mL/sec (P = .015). There was a mean prostate-specific antigen reduction of 2.27 ng/mL (P = .072) and a mean prostate volume decrease of 26.5 mL (P = .0001) by ultrasound and 28.9 mL (P = .008) by magnetic resonance imaging. There was one major complication (a 1.5-cm(2) ischemic area of the bladder wall) and four clinical failures (28.6%).<br />Conclusions: In this small group of patients, PAE was a feasible procedure, with preliminary results and short-term follow-up suggesting good symptom control without sexual dysfunction in suitable candidates, associated with a reduction in prostate volume.<br /> (Copyright © 2011 SIR. Published by Elsevier Inc. All rights reserved.)
- Subjects :
- Aged
Aged, 80 and over
Arteries
Biopsy
Feasibility Studies
Humans
Ischemia etiology
Magnetic Resonance Imaging
Male
Middle Aged
Organ Size
Penile Erection
Pilot Projects
Polyvinyl Alcohol adverse effects
Portugal
Prospective Studies
Prostate diagnostic imaging
Prostate pathology
Prostate-Specific Antigen blood
Prostatic Hyperplasia diagnosis
Prostatic Hyperplasia physiopathology
Prostatic Hyperplasia psychology
Quality of Life
Recovery of Function
Time Factors
Treatment Outcome
Ultrasonography
Urinary Bladder blood supply
Urodynamics
Embolization, Therapeutic adverse effects
Polyvinyl Alcohol administration & dosage
Prostate blood supply
Prostatic Hyperplasia therapy
Subjects
Details
- Language :
- English
- ISSN :
- 1535-7732
- Volume :
- 22
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Journal of vascular and interventional radiology : JVIR
- Publication Type :
- Academic Journal
- Accession number :
- 21195898
- Full Text :
- https://doi.org/10.1016/j.jvir.2010.09.030