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A new peptide motif in the formation of supramolecular double helices.

Authors :
Jana P
Maity S
Maity SK
Haldar D
Source :
Chemical communications (Cambridge, England) [Chem Commun (Camb)] 2011 Feb 21; Vol. 47 (7), pp. 2092-4. Date of Electronic Publication: 2010 Dec 24.
Publication Year :
2011

Abstract

The single crystal X-ray diffraction studies of a new tripeptide motif Boc-Tyr-Aib-Xaa-OMe (Xaa = Leu/Ile/Ala) reveal that the peptides adopt β-turn conformations which self-assemble to form a supramolecular double helical structure using various non-covalent interactions in the solid state and the peptides exhibit a type-III N(2) sorption isotherm.

Details

Language :
English
ISSN :
1364-548X
Volume :
47
Issue :
7
Database :
MEDLINE
Journal :
Chemical communications (Cambridge, England)
Publication Type :
Academic Journal
Accession number :
21186386
Full Text :
https://doi.org/10.1039/c0cc04244g