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In vitro susceptibilities of oxacillin-resistant Staphylococcus aureus to dapsone and sulfamethoxazole alone and in combination with trimethoprim.

Authors :
Lambertus MW
Kwok RY
Mulligan ME
Source :
Antimicrobial agents and chemotherapy [Antimicrob Agents Chemother] 1990 Jul; Vol. 34 (7), pp. 1453-5.
Publication Year :
1990

Abstract

The in vitro activity of trimethoprim plus dapsone against oxacillin-resistant Staphylococcus aureus was comparable to that of trimethoprim plus sulfamethoxazole. Because of its different pharmacologic properties, dapsone may be a useful agent in combination with trimethoprim for the treatment of patients colonized with oxacillin-resistant S. aureus.

Details

Language :
English
ISSN :
0066-4804
Volume :
34
Issue :
7
Database :
MEDLINE
Journal :
Antimicrobial agents and chemotherapy
Publication Type :
Academic Journal
Accession number :
2117420
Full Text :
https://doi.org/10.1128/AAC.34.7.1453