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Phytoconstituents from Vitex agnus-castus fruits.
- Source :
-
Fitoterapia [Fitoterapia] 2011 Jun; Vol. 82 (4), pp. 528-33. Date of Electronic Publication: 2010 Dec 13. - Publication Year :
- 2011
-
Abstract
- A new labdane-diterpene, viteagnusin I (1), together with 23 known phytoconstituents were isolated from the fruits of Vitex agnus-castus L, and their structures characterized by spectroscopic methods (NMR and MS). The known compounds include ten flavonoids, five terpenoids, three neolignans, and four phenolic compounds, as well as one glyceride. Biological evaluation identified apigenin, 3-methylkaempferol, luteolin, and casticin as weak ligands of delta and mu opioid receptors, exhibiting dose-dependent receptor binding.<br /> (Copyright © 2011 Elsevier B.V. All rights reserved.)
- Subjects :
- Diterpenes chemistry
Drugs, Chinese Herbal chemistry
Flavonoids isolation & purification
Fruit chemistry
Lignans isolation & purification
Magnetic Resonance Spectroscopy
Molecular Structure
Phenols isolation & purification
Spectrometry, Mass, Electrospray Ionization
Terpenes isolation & purification
Diterpenes isolation & purification
Vitex chemistry
Subjects
Details
- Language :
- English
- ISSN :
- 1873-6971
- Volume :
- 82
- Issue :
- 4
- Database :
- MEDLINE
- Journal :
- Fitoterapia
- Publication Type :
- Academic Journal
- Accession number :
- 21163339
- Full Text :
- https://doi.org/10.1016/j.fitote.2010.12.003