Copper-catalyzed tandem reactions of 1-(2-iodoary)-2-yn-1-ones with isocyanides for the synthesis of 4-oxo-indeno[1,2-b]pyrroles.

Authors :: Cai Q
Zhou F
Xu T
Fu L
Ding K
Source :: Organic letters [Org Lett] 2011 Jan 21; Vol. 13 (2), pp. 340-3. Date of Electronic Publication: 2010 Dec 17.
Publication Year :: 2011
Abstract: A novel copper-catalyzed tandem reaction of 1-(2-iodoaryl)-2-yn-1-ones with isocyanides is described. The reaction is through a formal [3 + 2] cycloaddition/coupling tandem process and leads to efficient formation of 4-oxo-indeno[1,2-b]pyrroles.

Subjects :: Catalysis
Combinatorial Chemistry Techniques
Cyclization
Heterocyclic Compounds, 3-Ring chemistry
Pyrroles chemistry
Alkynes chemistry
Copper chemistry
Cyanides chemistry
Heterocyclic Compounds, 3-Ring chemical synthesis
Pyrroles chemical synthesis

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