Ring transformation of unsaturated N-bridgehead fused pyrimidin-4(3H)-ones: role of repulsive electrostatic nonbonded interaction.

Authors :: Molnár A
Mucsi Z
Vlád G
Simon K
Holczbauer T
Podányi B
Faigl F
Hermecz I
Source :: The Journal of organic chemistry [J Org Chem] 2011 Jan 21; Vol. 76 (2), pp. 696-9. Date of Electronic Publication: 2010 Dec 15.
Publication Year :: 2011
Abstract: Thermal ring transformation ability of unsaturated N-bridgehead fused pyrimidin-4(3H)-ones A is governed by both the steric and the electrostatic interactions between the oxygen of the carbonyl group and the substituent in the peri position.

Subjects :: Cyclization
Magnetic Resonance Spectroscopy
Molecular Structure
Cycloparaffins chemistry
Heterocyclic Compounds, 2-Ring chemistry
Pyrimidinones chemistry

Full Text Access

Tools