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HIV/STI co-infections, syphilis incidence, and hepatitis B vaccination: the Buenos Aires cohort of men who have sex with men.
- Source :
-
AIDS care [AIDS Care] 2010 Dec; Vol. 22 (12), pp. 1459-65. - Publication Year :
- 2010
-
Abstract
- In a previous cohort study among 327 men who have sex with men (MSM) in Buenos Aires, an HIV incidence rate of 3.9 per 100 persons-year was reported. Using data from this study, we determined: (a) HIV/STI co-infections; (b) clinical manifestations of incident HIV infections; (c) syphilis incidence and its associated risk factors; and (d) adherence and immune response to hepatitis B virus (HBV) vaccine. During the cohort study, 12 incident HIV infections were found. Within this group, HIV infection alone was most frequent (42%), followed by co-infection of HIV/HBV (33%), and triple co-infection of HIV/HBV/syphilis (25%). The most frequent clinical manifestations among incident HIV cases were: pharyngitis, fever, lymphadenopathy, asthenia, and myalgia. Seven new syphilis infections were detected yielding an incidence rate of 2.4 (95% CI=1.07 - 4.73) per 100 persons-year. Sex work was the only significant risk factor associated with syphilis seroconversion (hazard rate=10.93, p-value=0.033). Only 7% of cohort participants reported having received HBV vaccine. Ninety-percent of the 204 cohort members who agreed to be vaccinated completed the HBV vaccination schedule with an immune response rate of 85%. Our findings suggest the need to increase the access to serologic testing for STI and HBV immunization, as well as the developing of effective HIV/STI behavioral and educational prevention programs among MSM in Buenos Aires.
- Subjects :
- Adult
Argentina epidemiology
Cohort Studies
HIV Infections complications
Hepatitis B complications
Hepatitis B prevention & control
Humans
Incidence
Male
Sexual Partners
Syphilis complications
HIV Infections epidemiology
Hepatitis B epidemiology
Hepatitis B Vaccines administration & dosage
Homosexuality, Male
Syphilis epidemiology
Subjects
Details
- Language :
- English
- ISSN :
- 1360-0451
- Volume :
- 22
- Issue :
- 12
- Database :
- MEDLINE
- Journal :
- AIDS care
- Publication Type :
- Academic Journal
- Accession number :
- 21154033
- Full Text :
- https://doi.org/10.1080/09540121003758556