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[Prophylactic and therapeutic efficacies of Ingavirin, a novel Russian chemotherapeutic, with respect to influenza pathogen A (H5N1)].

Authors :
Loginova SIa
Borisevich SV
Shkliaeva OM
Maksimov VA
Bondarev VP
Nebol'sin VE
Source :
Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] [Antibiot Khimioter] 2010; Vol. 55 (7-8), pp. 10-2.
Publication Year :
2010

Abstract

The experimental study of the Ingavirin efficacy against the influenza virus A (H5N1) on intranasally-infected albino mice vs. Tamiflue and Arbidol showed that when used for the prophylaxis, urgent prophylaxis and therapy it was effective in the protectiom of the animals from death. The efficient dose for the prophylaxis of the influenza infection was 5 mg/kg (protective efficacy of 46.7%) and for the urgent prophylaxis and therapy it was 15 mg/kg (protective efficacy of 40.0 and 35.0% respectively).

Details

Language :
Russian
ISSN :
0235-2990
Volume :
55
Issue :
7-8
Database :
MEDLINE
Journal :
Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic]
Publication Type :
Academic Journal
Accession number :
21140557