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[Prophylactic and therapeutic efficacies of Ingavirin, a novel Russian chemotherapeutic, with respect to influenza pathogen A (H5N1)].
- Source :
-
Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] [Antibiot Khimioter] 2010; Vol. 55 (7-8), pp. 10-2. - Publication Year :
- 2010
-
Abstract
- The experimental study of the Ingavirin efficacy against the influenza virus A (H5N1) on intranasally-infected albino mice vs. Tamiflue and Arbidol showed that when used for the prophylaxis, urgent prophylaxis and therapy it was effective in the protectiom of the animals from death. The efficient dose for the prophylaxis of the influenza infection was 5 mg/kg (protective efficacy of 46.7%) and for the urgent prophylaxis and therapy it was 15 mg/kg (protective efficacy of 40.0 and 35.0% respectively).
- Subjects :
- Animals
Caproates
Humans
Indoles therapeutic use
Influenza A Virus, H5N1 Subtype
Mice
Mice, Inbred Strains
Oseltamivir therapeutic use
Amides therapeutic use
Antiviral Agents therapeutic use
Dicarboxylic Acids therapeutic use
Imidazoles therapeutic use
Influenza, Human prevention & control
Orthomyxoviridae Infections prevention & control
Subjects
Details
- Language :
- Russian
- ISSN :
- 0235-2990
- Volume :
- 55
- Issue :
- 7-8
- Database :
- MEDLINE
- Journal :
- Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic]
- Publication Type :
- Academic Journal
- Accession number :
- 21140557