[Study on supercritical CO2 extraction of flavonoids from Cynomorium songaricum].

Objective: To study the extraction technology of flavonoids from Cynomorium songaricum by supercritical CO2 extraction.
Methods: The effects of pressure, temperature, time, concentration of alcohol, dosage of chemical preparation, flux of CO2 and particle size were studied by single factor analysis and orthogonal test.
Results: The optimized conditions were as follows: particle size 60 - 80 sieve mesh, the pressure was 30 MPa, the temperature was 50 degrees C, the time was 75 min, concentration of alcohol was 50%, entrainment rate was 8%, flux of CO2 was 5 mL/min. The total flavonoids yield could reach 21.18% under the above conditions.
Conclusion: This method is simple, rapid and higher extraction yield, so it is suitable for the extraction of flavonoids from Cynomorium songaricum.