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[Periodic fever: a description of twelve patients with periodic fever, aphthous stomatitis, pharyngitis and cervical adenitis (PFAPA)].

Authors :
De Cunto C
Britos M
Eymann A
Deltetto N
Liberatore D
Source :
Archivos argentinos de pediatria [Arch Argent Pediatr] 2010 Oct; Vol. 108 (5), pp. 445-8.
Publication Year :
2010

Abstract

PFAPA is a periodic fever syndrome characterized by: fever, aphthous stomatitis, pharyngitis and cervical adenitis. It is one of the autoinflammatory syndromes, but yet of unknown etiology. Our aim is to report our experience, describe clinical manifestations, laboratory findings, relapses occurrence and response to treatment. We present 12 PFAPA patients. Median age at onset: 1.15 years, mean duration of febrile episodes: 4 days, and relapses at regular intervals. All children received prednisone (1-2 mg/kg/dose) one to two doses, 9 patients responded immediately after the first dose and all experienced a lower periodicity of attacks. PFAPA is the most frequent periodic fever syndrome. To our knowledge, there are no other local series of PFAPA patients published. Recognizing this syndrome will prevent from ordering unnecessary studies and will favor family coping.

Details

Language :
Spanish; Castilian
ISSN :
1668-3501
Volume :
108
Issue :
5
Database :
MEDLINE
Journal :
Archivos argentinos de pediatria
Publication Type :
Academic Journal
Accession number :
21132234
Full Text :
https://doi.org/10.1590/S0325-00752010000500011