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Lymph node metastasis in grossly apparent clinical stage Ia epithelial ovarian cancer: Hacettepe experience and review of literature.
- Source :
-
World journal of surgical oncology [World J Surg Oncol] 2010 Nov 30; Vol. 8, pp. 106. Date of Electronic Publication: 2010 Nov 30. - Publication Year :
- 2010
-
Abstract
- Background: Lymphadenectomy is an integral part of the staging system of epithelial ovarian cancer. However, the extent of lymphadenectomy in the early stages of ovarian cancer is controversial. The objective of this study was to identify the lymph node involvement in unilateral epithelial ovarian cancer apparently confined to the one ovary (clinical stage Ia).<br />Methods: A prospective study of clinical stage I ovarian cancer patients is presented. Patient's characteristics and tumor histopathology were the variables evaluated.<br />Results: Thirty three ovarian cancer patients with intact ovarian capsule were evaluated. Intraoperatively, neither of the patients had surface involvement, adhesions, ascites or palpable lymph nodes (supposed to be clinical stage Ia). The mean age of the study group was 55.3 ± 11.8. All patients were surgically staged and have undergone a systematic pelvic and paraaortic lymphadenectomy. Final surgicopathologic reports revealed capsular involvement in seven patients (21.2%), contralateral ovarian involvement in two (6%) and omental metastasis in one (3%) patient. There were two patients (6%) with lymph node involvement. One of the two lymph node metastasis was solely in paraaortic node and the other metastasis was in ipsilateral pelvic lymph node. Ovarian capsule was intact in all of the patients with lymph node involvement and the tumor was grade 3.<br />Conclusion: In clinical stage Ia ovarian cancer patients, there may be a risk of paraaortic and pelvic lymph node metastasis. Further studies with larger sample size are needed for an exact conclusion.
- Subjects :
- Adenocarcinoma surgery
Adult
Aged
Aged, 80 and over
Carcinoma, Ovarian Epithelial
Female
Humans
Lymph Node Excision
Lymph Nodes pathology
Lymph Nodes surgery
Lymphatic Metastasis
Middle Aged
Neoplasm Staging
Neoplasms, Glandular and Epithelial pathology
Neoplasms, Glandular and Epithelial surgery
Ovarian Neoplasms pathology
Ovarian Neoplasms surgery
Pelvis pathology
Prognosis
Prospective Studies
Adenocarcinoma secondary
Subjects
Details
- Language :
- English
- ISSN :
- 1477-7819
- Volume :
- 8
- Database :
- MEDLINE
- Journal :
- World journal of surgical oncology
- Publication Type :
- Academic Journal
- Accession number :
- 21114870
- Full Text :
- https://doi.org/10.1186/1477-7819-8-106