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A new neuroprotective bakkenolide from the rhizome of Peatasites tatewakianus.
- Source :
-
Fitoterapia [Fitoterapia] 2011 Apr; Vol. 82 (3), pp. 401-4. Date of Electronic Publication: 2010 Nov 25. - Publication Year :
- 2011
-
Abstract
- Constituents of the fruits of Peatasites tatewakianus were investigated. A new compound, namely bakkenolide-VI (1), was isolated. The structures was elucidated on the basis of 1D, 2D NMR, TOF-MS and ESI-MS techniques, and physicochemical properties. The neuroprotective activity of the new compound was assayed with primary cultured neurons exposed to oxygen-glucose deprivation and oxidative insults.<br /> (Copyright © 2010 Elsevier B.V. All rights reserved.)
- Subjects :
- Cell Culture Techniques
Fruit
Glucose deficiency
Molecular Structure
Oxidative Stress drug effects
Oxygen metabolism
Plant Extracts chemistry
Rhizome chemistry
Sesquiterpenes chemistry
Sesquiterpenes isolation & purification
Spectrum Analysis methods
Neurons drug effects
Neuroprotective Agents pharmacology
Petasites chemistry
Plant Extracts pharmacology
Sesquiterpenes pharmacology
Subjects
Details
- Language :
- English
- ISSN :
- 1873-6971
- Volume :
- 82
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- Fitoterapia
- Publication Type :
- Academic Journal
- Accession number :
- 21111792
- Full Text :
- https://doi.org/10.1016/j.fitote.2010.11.020