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[The comparison of the WHO standard rabies immunoglobulin and the national standard human rabies immunoglobulin used in the rapid fluorescent focus inhibition test (RFFIT)].

Authors :
Yu PC
Shen XX
Lv XJ
Shan H
Tang Q
Source :
Zhonghua shi yan he lin chuang bing du xue za zhi = Zhonghua shiyan he linchuang bingduxue zazhi = Chinese journal of experimental and clinical virology [Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi] 2010 Apr; Vol. 24 (2), pp. 91-3.
Publication Year :
2010

Abstract

Objective: Compare the difference of the results referred to the WHO standard rabies immunoglobulin and the national standard human rabies immunoglobulin used in the rapid fluorescent focus inhibition test (RFFIT).<br />Methods: Setting the WHO standard immunoglobulin and the national standard immunoglobulin in the same system and testing 12 human serum at the same time. Compare the fluorescence percentage of the two different standard immunoglobulin; compare the 12 serum results calculated from the two different standard immunoglobulin used the calculation formula of neutralization antibody titer.<br />Results: The Results display that the 50% percent of the two standard immunoglobulin are all between the fifth and the sixth well, but the percentage of the national standard immunoglobulin is lower than the WHO one. The same testserum result calculated from the WHO standard immunoglobulin is little higher than the national one.<br />Conclusion: There is difference in the WHO standard immunoglobulin and the national one, but there is no influence in the results.

Details

Language :
Chinese
ISSN :
1003-9279
Volume :
24
Issue :
2
Database :
MEDLINE
Journal :
Zhonghua shi yan he lin chuang bing du xue za zhi = Zhonghua shiyan he linchuang bingduxue zazhi = Chinese journal of experimental and clinical virology
Publication Type :
Academic Journal
Accession number :
21110422