Small-molecule inhibitors of the ERK signaling pathway: Towards novel anticancer therapeutics.

Subjects

Subjects :

Animals
Antineoplastic Agents metabolism
Cell Line, Tumor
Enzyme Inhibitors metabolism
Extracellular Signal-Regulated MAP Kinases metabolism
Humans
MAP Kinase Signaling System drug effects
Mice
Neoplasms drug therapy
Protein Binding drug effects
Quantitative Structure-Activity Relationship
Signal Transduction drug effects
Small Molecule Libraries metabolism
raf Kinases metabolism
Antineoplastic Agents pharmacology
Enzyme Inhibitors pharmacology
Extracellular Signal-Regulated MAP Kinases antagonists & inhibitors
Small Molecule Libraries pharmacology
raf Kinases antagonists & inhibitors

Details

Language :

English

ISSN :

1860-7187

Volume :

6

Issue :

1

Database :

MEDLINE

Journal :

ChemMedChem

Publication Type :

Academic Journal

Accession number :

21110380

Full Text :

https://doi.org/10.1002/cmdc.201000354