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The Mediterranean and Dietary Approaches to Stop Hypertension (DASH) diets and colorectal cancer.
- Source :
-
The American journal of clinical nutrition [Am J Clin Nutr] 2010 Dec; Vol. 92 (6), pp. 1429-35. - Publication Year :
- 2010
-
Abstract
- Background: Although the Mediterranean diet has been studied for cancer mortality and the Dietary Approaches to Stop Hypertension (DASH) diet shares similarities with the Mediterranean diet, few studies have specifically examined these 2 diets and incident colorectal cancer.<br />Objective: The objective was to prospectively assess the association between the Alternate Mediterranean Diet (aMed) and the DASH-style diet scores and risk of colorectal cancer in middle-aged men and women.<br />Design: A total of 87,256 women and 45,490 men (age 30-55 y for women and 40-75 y for men at baseline) without a history of cancer were followed for ≤ 26 y. The aMed and DASH scores were calculated for each participant by using dietary information that was assessed ≤ 7 times during follow-up. Relative risks (RRs) for colorectal cancer were computed with adjustment for potential confounders.<br />Results: We documented 1432 cases of incident colorectal cancer among women and 1032 cases in men. Comparing top with bottom quintiles of the DASH score, the pooled RR for total colorectal cancer was 0.80 (95% CI: 0.70, 0.91; P for trend = 0.0001). The corresponding RR for DASH score and colon cancer was 0.81 (95% CI: 0.69, 0.95; P for trend = 0.002). There was a suggestion of an inverse association with rectal cancer with a pooled RR of 0.73 (95% CI: 0.55, 0.98; P for trend = 0.31) when comparing top with bottom quintiles of DASH score. No association was observed with aMed score.<br />Conclusion: Adherence to the DASH diet (which involves higher intakes of whole grains, fruit, and vegetables; moderate amounts of low-fat dairy; and lower amounts of red or processed meats, desserts, and sweetened beverages) was associated with a lower risk of colorectal cancer.
- Subjects :
- Adult
Aged
Body Mass Index
Colorectal Neoplasms epidemiology
Colorectal Neoplasms etiology
Female
Humans
Incidence
Male
Middle Aged
Proportional Hazards Models
Prospective Studies
Risk Factors
Sex Factors
Colorectal Neoplasms prevention & control
Diet
Diet, Mediterranean
Hypertension diet therapy
Subjects
Details
- Language :
- English
- ISSN :
- 1938-3207
- Volume :
- 92
- Issue :
- 6
- Database :
- MEDLINE
- Journal :
- The American journal of clinical nutrition
- Publication Type :
- Academic Journal
- Accession number :
- 21097651
- Full Text :
- https://doi.org/10.3945/ajcn.2010.29242