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Confirmation of putative HIV-1 group P in Cameroon.

Authors :
Vallari A
Holzmayer V
Harris B
Yamaguchi J
Ngansop C
Makamche F
Mbanya D
Kaptué L
Ndembi N
Gürtler L
Devare S
Brennan CA
Source :
Journal of virology [J Virol] 2011 Feb; Vol. 85 (3), pp. 1403-7. Date of Electronic Publication: 2010 Nov 17.
Publication Year :
2011

Abstract

We report the second human immunodeficiency virus (HIV) belonging to the new HIV type 1 (HIV-1) group P lineage that is closely related to the simian immunodeficiency virus found in gorillas. This virus was identified in an HIV-seropositive male hospital patient in Cameroon, confirming that the group P virus is circulating in humans. Results from screening 1,736 HIV-seropositive specimens collected in Cameroon indicate that HIV-1 group P infections are rare, accounting for only 0.06% of HIV infections. Despite its rarity, group P shows evidence of adaptation to humans.

Details

Language :
English
ISSN :
1098-5514
Volume :
85
Issue :
3
Database :
MEDLINE
Journal :
Journal of virology
Publication Type :
Academic Journal
Accession number :
21084486
Full Text :
https://doi.org/10.1128/JVI.02005-10