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Prospective diary evaluation of unexplained abdominal pain and bowel dysfunction: a population-based colonoscopy study.
- Source :
-
Digestive diseases and sciences [Dig Dis Sci] 2011 May; Vol. 56 (5), pp. 1444-51. Date of Electronic Publication: 2010 Nov 10. - Publication Year :
- 2011
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Abstract
- Introduction: Diagnostic criteria for irritable bowel syndrome (IBS) have not been validated by prospective symptom diary. We investigated the bowel patterns in community subjects with and without non-organic abdominal pain, and compared the symptoms with subjects fulfilling the Rome II criteria (IBS).<br />Methods: From the Swedish population register, a random sample completed an abdominal symptom questionnaire. Responders were subsequently invited for a clinical evaluation and offered a colonoscopy regardless of whether they had abdominal symptoms or not. A total of 268 subjects underwent colonoscopy, clinical evaluation by gastroenterologist, laboratory investigations, and completed the Rome questionnaire and prospective gastrointestinal (GI) symptom diaries for 1 week. Twenty-three subjects of 268 were excluded due to organic GI disease.<br />Results: Subjects recorded 2,194 bowel movements and 370 abdominal pain episodes on 1,504 days. Subjects with pain in the diary (n = 81) had higher stool frequency (P = 0.01), more urgency (P = 0.0002), feelings of incomplete evacuation (P = 0.0002), nausea (P = 0.0009), and abdominal bloating (P = 0.0005) than subjects without pain (n = 151). Twenty-eight subjects (12%) fulfilled the Rome II criteria for IBS. Together, they had 96 pain episodes but only 4% were improved by defecation; 29% of the pain episodes started or worsened after a meal. Subjects with IBS and other subjects with non-organic abdominal pain (n = 64) exhibited no differences in terms of the proportions of pain episodes improved by defecation, bloating, stool frequency, consistency, or defecatory symptoms.<br />Conclusions: Current criteria for IBS that rely on recall of the relationship between abdominal pain and bowel disturbance may overcall this association when measured prospectively.
- Subjects :
- Abdominal Pain epidemiology
Adult
Age Distribution
Aged
Female
Humans
Irritable Bowel Syndrome diagnosis
Irritable Bowel Syndrome epidemiology
Male
Medical Records
Middle Aged
Sex Distribution
Sweden epidemiology
Young Adult
Abdominal Pain etiology
Colonoscopy
Irritable Bowel Syndrome complications
Subjects
Details
- Language :
- English
- ISSN :
- 1573-2568
- Volume :
- 56
- Issue :
- 5
- Database :
- MEDLINE
- Journal :
- Digestive diseases and sciences
- Publication Type :
- Academic Journal
- Accession number :
- 21063776
- Full Text :
- https://doi.org/10.1007/s10620-010-1468-y