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[Correlation analysis of two serum specific IgE test systems and skin prick test in allergic rhinitis patients].

[Correlation analysis of two serum specific IgE test systems and skin prick test in allergic rhinitis patients].

Authors :
Jiang XD
Li GY
Sha JC
Zhu XW
Meng CD
Dong Z
Zhu DD
Source :
Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery [Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi] 2010 Aug; Vol. 45 (8), pp. 652-5.
Publication Year :
2010

Abstract

Objective: To evaluate the correlation between two serum specific IgE and skin prick test (SPT) for the diagnosis of allergic rhinitis.<br />Methods: Two hundred and sixteen patients were referred to the allergist for a suspected allergic rhinitis between June and October in 2009. Patients were classified as positive for inhalant allergy if they had a positive clinical history and a related positive SPT for the suspected inhalant allergen. Statistical analysis was performed using SPSS13.0 software.<br />Results: One hundred and fifty-eight patients had a positive SPT, comparing with the SPT, the diagnostic indexes (accuracy, sensitivity, specificity) of the ImmunoCAP system and the AllergyScreen system were 0.810 and 0.819, 0.872 and 0.780, 0.741 and 0.862 respectively. The accuracy was similar between the two systems (χ(2) = 0.112, P > 0.05). The ImmunoCAP system had a higher sensitivity (χ(2) = 7.361, P < 0.05). The AllergyScreen system had a higher specificity (χ(2) = 10.222, P < 0.05).<br />Conclusions: This data supported the use of ImmunoCAP system and AllergyScreen system to identify potentially significant individual allergens in the diagnosis of allergic rhinitis. The ImmunoCAP system had a higher sensitivity. The AllergyScreen system had a higher specificity. The AllergyScreen system can be used as a complementary with the ImmunoCAP system.

Details

Language :
Chinese
ISSN :
1673-0860
Volume :
45
Issue :
8
Database :
MEDLINE
Journal :
Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery
Publication Type :
Academic Journal
Accession number :
21055241