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Witkop tooth and nail syndrome: a report of three cases in a family.
- Source :
-
Pediatric dermatology [Pediatr Dermatol] 2011 May-Jun; Vol. 28 (3), pp. 281-5. Date of Electronic Publication: 2010 Nov 05. - Publication Year :
- 2011
-
Abstract
- Witkop tooth and nail syndrome is a rare autosomal dominant ectodermal dysplasia manifested by hypodontia and nail dysplasia. Tooth shape may vary, and conical and narrow crowns are common. Mandibular incisors, second molars, and maxillary canines are the most frequently missing teeth. Nail dysplasia affects the fingernails and especially the toenails and is often more severe in childhood. Nails may be spoon-shaped, ridged, slow-growing, and easily broken. We examined an Eastern Mediterranean family in which three siblings (two girls, one boy) had this syndrome. The severity of finger and toenail anomalies varied. The children's mother had no Witkop-related abnormalities, but their father was reported to have dental and nail anomalies. Early intervention is recommended to manage orofacial disfigurement and avoid negative social consequences for these children.<br /> (© 2010 Wiley Periodicals, Inc.)
- Subjects :
- Adolescent
Anodontia diagnostic imaging
Bicuspid diagnostic imaging
Child, Preschool
Family Health
Female
Humans
Incisor diagnostic imaging
Male
Nails, Malformed diagnostic imaging
Radiography
Siblings
Anodontia pathology
Bicuspid abnormalities
Incisor abnormalities
Nails pathology
Nails, Malformed pathology
Subjects
Details
- Language :
- English
- ISSN :
- 1525-1470
- Volume :
- 28
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- Pediatric dermatology
- Publication Type :
- Academic Journal
- Accession number :
- 21054511
- Full Text :
- https://doi.org/10.1111/j.1525-1470.2010.01198.x