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Disseminated Mycobacterium avium subspecies infection in a cat.
- Source :
-
Journal of feline medicine and surgery [J Feline Med Surg] 2011 Feb; Vol. 13 (2), pp. 125-8. Date of Electronic Publication: 2010 Oct 30. - Publication Year :
- 2011
-
Abstract
- An 18-month-old neutered male domestic shorthair cat, domiciled in the southwest of France, was first presented having suffered for a few days from dysorexia and vomiting. Abdominal palpation revealed lymph node enlargement. Cytological examinations of a fine needle aspirate demonstrated granulomatous inflammation with many non-staining elements consistent with mycobacteria. Diagnosis was confirmed by culture and polymerase chain reaction and Mycobacterium avium subspecies was isolated. Treatment was initiated with marbofloxacin, rifampicin and cefoxitin. There was a rapid clinical improvement. The cat suddenly died 2 months later. The main hypothesis is the administration of an inappropriate combination therapy that leads to the development of mycobacterial resistance. A volvulus and acute peritonitis secondary to the significant enlargement of a mesenteric lymph node were present at necropsy. Histopathological analysis of mesenteric lymph node, liver and spleen revealed multicentric granulomatous and severely necrotic lesions with numerous Ziehl-Neelsen positive intracytoplasmic elements.<br /> (Copyright © 2010 ISFM and AAFP. Published by Elsevier Ltd. All rights reserved.)
- Subjects :
- Animals
Anti-Bacterial Agents adverse effects
Cat Diseases drug therapy
Cats
Cefoxitin adverse effects
Drug Resistance, Multiple, Bacterial
Drug Therapy, Combination adverse effects
Drug Therapy, Combination veterinary
Fatal Outcome
Fluoroquinolones adverse effects
Male
Mycobacterium avium isolation & purification
Rifampin adverse effects
Tuberculosis drug therapy
Tuberculosis microbiology
Cat Diseases microbiology
Mycobacterium avium classification
Tuberculosis veterinary
Subjects
Details
- Language :
- English
- ISSN :
- 1532-2750
- Volume :
- 13
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- Journal of feline medicine and surgery
- Publication Type :
- Academic Journal
- Accession number :
- 21036643
- Full Text :
- https://doi.org/10.1016/j.jfms.2010.09.002