Back to Search
Start Over
Synthesis of an ortho-triazacyclophane: N,N',N''-trimethyltribenzo-1,4,7-triazacyclononatriene.
- Source :
-
The Journal of organic chemistry [J Org Chem] 2010 Nov 19; Vol. 75 (22), pp. 7887-92. Date of Electronic Publication: 2010 Oct 25. - Publication Year :
- 2010
-
Abstract
- N,N',N''-trimethyltribenzo-1,4,7-triazacyclononatriene has been synthesized via sequential palladium-catalyzed Buchwald-Hartwig N-arylation reactions affording the 9-membered triaza o-cyclophane in 35% overall yield. An X-ray crystal structure shows the new cyclophane to have a C2-symmetric saddle conformation, as compared to the crown conformation exhibited by the related carbocyclic cyclotriveratrylene (CTV).
- Subjects :
- Aza Compounds chemistry
Crystallography, X-Ray
Heterocyclic Compounds, 2-Ring chemistry
Heterocyclic Compounds, 3-Ring chemistry
Molecular Conformation
Molecular Structure
Polycyclic Compounds chemistry
Aza Compounds chemical synthesis
Heterocyclic Compounds, 2-Ring chemical synthesis
Heterocyclic Compounds, 3-Ring chemical synthesis
Palladium chemistry
Polycyclic Compounds chemical synthesis
Subjects
Details
- Language :
- English
- ISSN :
- 1520-6904
- Volume :
- 75
- Issue :
- 22
- Database :
- MEDLINE
- Journal :
- The Journal of organic chemistry
- Publication Type :
- Academic Journal
- Accession number :
- 20973522
- Full Text :
- https://doi.org/10.1021/jo1017074