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Chronic granulocytic leukaemia. A study of 160 cases.
- Source :
-
The Journal of the Association of Physicians of India [J Assoc Physicians India] 1990 Dec; Vol. 38 (12), pp. 899-902. - Publication Year :
- 1990
-
Abstract
- Chronic granulocytic leukaemia (CGL) is the commonest leukaemia among adults in India. Case records of 183 CGL patients diagnosed between 1975 and 1985 were reviewed. The median age at diagnosis was 40.5 years. Most patients presented with weakness, fullness in the left upper abdomen and fever. Splenomegaly and hepatomegaly were present in 90% and 48% respectively. Patients were treated with oral, intermittent busulphan with monitoring of total leucocyte count. Overall, 87 patients expired, including 63 (72%) due to blast crisis. The median survival was 33 months from diagnosis and 44 months from the onset of symptoms.
- Subjects :
- Adolescent
Adult
Aged
Blast Crisis blood
Busulfan adverse effects
Busulfan therapeutic use
Female
Follow-Up Studies
Hepatomegaly diagnosis
Humans
India
Leukemia, Myelogenous, Chronic, BCR-ABL Positive blood
Leukemia, Myelogenous, Chronic, BCR-ABL Positive drug therapy
Leukocyte Count
Male
Middle Aged
Splenomegaly diagnosis
Leukemia, Myelogenous, Chronic, BCR-ABL Positive diagnosis
Subjects
Details
- Language :
- English
- ISSN :
- 0004-5772
- Volume :
- 38
- Issue :
- 12
- Database :
- MEDLINE
- Journal :
- The Journal of the Association of Physicians of India
- Publication Type :
- Academic Journal
- Accession number :
- 2096123