GTPases involved in vesicular trafficking: structures and mechanisms.

Authors :: Itzen A
Goody RS
Source :: Seminars in cell & developmental biology [Semin Cell Dev Biol] 2011 Feb; Vol. 22 (1), pp. 48-56. Date of Electronic Publication: 2010 Oct 15.
Publication Year :: 2011
Abstract: Several types of GTPases play important roles in intracellular vesicular transport. These include the Rab and Arf families of the Ras superfamily, which are key regulators of several steps in the overall process. The basic structural and mechanistic properties of these proteins and their interactions with partner proteins and membranes are reviewed and compared in this article.<br /> (Copyright © 2010 Elsevier Ltd. All rights reserved.)