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[Hemorheological effects of thiophane on tetrachloromethane induced hepatic damage].

Authors :
Smol'iakova VI
Plotnikov MB
Chernysheva GA
Ivanov IS
Prosenko AE
Kandalintseva NV
Source :
Eksperimental'naia i klinicheskaia farmakologiia [Eksp Klin Farmakol] 2010 Aug; Vol. 73 (8), pp. 32-4.
Publication Year :
2010

Abstract

Carbon tetrachloride-induced hepatitis in rats is accompanied by blood hyperviscosity syndrome development. A course intragastric administration of thiophane under these conditions prevents the increase in whole blood viscosity by normalizing the microrheological indices (deformability and aggregation of erythrocytes), which is manifested by increasing oxygen availability for tissues.

Details

Language :
Russian
ISSN :
0869-2092
Volume :
73
Issue :
8
Database :
MEDLINE
Journal :
Eksperimental'naia i klinicheskaia farmakologiia
Publication Type :
Academic Journal
Accession number :
20919556