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[Antifertility actions of gossypol derivatives and analogues].

Authors :
Wang WH
Yu ZH
Cai M
Xu XM
Wu GP
Source :
Zhongguo yao li xue bao = Acta pharmacologica Sinica [Zhongguo Yao Li Xue Bao] 1990 May; Vol. 11 (3), pp. 268-71.
Publication Year :
1990

Abstract

This paper reports the results of 32 gossypol derivatives and analogues. Among 12 compounds screened by oral administration to male rats, only dipotassium gossypolate (NC030) exhibited an antifertility activity similar to gossypol. Among 24 compounds screened by injecting into pouches of cauda epididymides of rats, 10 exhibited spermicidal activities.

Details

Language :
Chinese
ISSN :
0253-9756
Volume :
11
Issue :
3
Database :
MEDLINE
Journal :
Zhongguo yao li xue bao = Acta pharmacologica Sinica
Publication Type :
Academic Journal
Accession number :
2088004