Back to Search
Start Over
[Antimicrobic and hemolytic activity of low-molecular metabolits of brown seaweed Laminaria cichorioides Miyabe].
- Source :
-
Prikladnaia biokhimiia i mikrobiologiia [Prikl Biokhim Mikrobiol] 2010 Jul-Aug; Vol. 46 (4), pp. 467-71. - Publication Year :
- 2010
-
Abstract
- Antimicrobial and hemolytic activity of ethanol extract of brown seaweed Laminaria cichorioides Miyabe, its lipophilic fractions, various classes of substances of lipophilic fraction, such as chlorophylls, fucoxanthin, monogalactosyldiacylglycerols, digalactosyldiacylglycerols, sulfoquinovosyldiacylglycerols, and fatty acids were investigated. The antimicrobial activity was studied by means of yeast cells Safale S-04 and Candida albicans CMM 455, fungi Aspergillus niger CMM 4634 and Fusarium oxysporum CMM 4639, bacteria Staphylococcus aureus ATCC 21027 (gram-positive) and Escherichia coli ATCC 15034 (gram-negative) which demonstrated selective sensitivity to the studied substances. Hemolytic activity was investigated at concentrations of substances in the range of 0.2-2000 microg/ml at different pH of erythrocyte suspension. All investigated substances caused hemolysis. The dependence of hemolytic activity of substances on pH of media was determined.
- Subjects :
- Animals
Anti-Infective Agents isolation & purification
Aspergillus niger drug effects
Candida albicans drug effects
Erythrocytes drug effects
Escherichia coli drug effects
Fusarium drug effects
Hemolysis
Hemolytic Agents isolation & purification
Mice
Staphylococcus aureus drug effects
Anti-Infective Agents pharmacology
Hemolytic Agents pharmacology
Laminaria chemistry
Subjects
Details
- Language :
- Russian
- ISSN :
- 0555-1099
- Volume :
- 46
- Issue :
- 4
- Database :
- MEDLINE
- Journal :
- Prikladnaia biokhimiia i mikrobiologiia
- Publication Type :
- Academic Journal
- Accession number :
- 20873173