Cellular sources and immune functions of interleukin-9.

Authors :: Noelle RJ
Nowak EC
Source :: Nature reviews. Immunology [Nat Rev Immunol] 2010 Oct; Vol. 10 (10), pp. 683-7. Date of Electronic Publication: 2010 Sep 17.
Publication Year :: 2010
Abstract: Interleukin-9 (IL-9) has attracted renewed interest owing to the identification of its expression by multiple T helper (T(H)) cell subsets, including T(H)2 cells, T(H)9 cells, T(H)17 cells and regulatory T (T(Reg)) cells. Here, we provide a broad overview of the conditions that are required for cells to produce IL-9 and describe the cellular targets and nature of the immune responses that are induced by IL-9.