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Ni-catalyzed reduction of inert C-O bonds: a new strategy for using aryl ethers as easily removable directing groups.

Authors :
Álvarez-Bercedo P
Martin R
Source :
Journal of the American Chemical Society [J Am Chem Soc] 2010 Dec 15; Vol. 132 (49), pp. 17352-3. Date of Electronic Publication: 2010 Sep 15.
Publication Year :
2010

Abstract

An efficient Ni-catalyzed protocol for the reductive cleavage of inert C-O bonds has been developed. The method is characterized by its simplicity and wide scope, thereby allowing the use of aryl ethers as easily removable directing groups in organic synthesis.

Details

Language :
English
ISSN :
1520-5126
Volume :
132
Issue :
49
Database :
MEDLINE
Journal :
Journal of the American Chemical Society
Publication Type :
Academic Journal
Accession number :
20843037
Full Text :
https://doi.org/10.1021/ja106943q