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Diels-Alder reactions of cyclic isoimidium salts.

Authors :
Boeckman RK Jr
Miller Y
Ryder TR
Source :
Organic letters [Org Lett] 2010 Oct 15; Vol. 12 (20), pp. 4524-7.
Publication Year :
2010

Abstract

Diels-Alder reactions of cyclic isoimidium salts are described. The corresponding cycloadducts are obtained with high regio- and stereoselectivity. The use of homochiral cyclic isoimidium salts delivers cycloadducts with excellent diastereoselectivity (>99:1) that can be efficiently converted to enantiomerically pure lactones.

Details

Language :
English
ISSN :
1523-7052
Volume :
12
Issue :
20
Database :
MEDLINE
Journal :
Organic letters
Publication Type :
Academic Journal
Accession number :
20843021
Full Text :
https://doi.org/10.1021/ol101831b