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Burkitt's lymphoma in pregnancy with bilateral breast involvement: case report with review of the literature.
- Source :
-
Onkologie [Onkologie] 2010; Vol. 33 (8-9), pp. 461-4. Date of Electronic Publication: 2010 Jul 26. - Publication Year :
- 2010
-
Abstract
- Background: Burkitt's lymphoma (BL) in pregnancy presenting with breast involvement is a rare clinical entity, and only 13 cases have been reported so far.<br />Case Report: We describe the case of a 28-year-old postpartum woman who presented with markedly enlarged breasts caused by BL. She was treated with 8 cycles of the CALGB 10002 regimen, as well as with irradiation to both breasts. After achieving a complete objective response, the patient received consolidation with high dose BEAM followed by autologous stem cell transplantation. 20 months after the initial diagnosis, our patient remains alive and relapse-free. Data extracted from the published case reports include information regarding demographic details, type of treatment, sites of disease, and survival. The clinical outcome of the reviewed cases was very unfavorable.<br />Conclusions: BL affecting breasts during pregnancy or lactation is a rare entity that requires a prompt diagnosis and an aggressive therapeutic approach.<br /> (Copyright © 2010 S. Karger AG, Basel.)
Details
- Language :
- English
- ISSN :
- 1423-0240
- Volume :
- 33
- Issue :
- 8-9
- Database :
- MEDLINE
- Journal :
- Onkologie
- Publication Type :
- Academic Journal
- Accession number :
- 20838063
- Full Text :
- https://doi.org/10.1159/000317344