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Development of photostable near-infrared cyanine dyes.

Authors :
Samanta A
Vendrell M
Das R
Chang YT
Source :
Chemical communications (Cambridge, England) [Chem Commun (Camb)] 2010 Oct 21; Vol. 46 (39), pp. 7406-8. Date of Electronic Publication: 2010 Sep 08.
Publication Year :
2010

Abstract

With the emerging interest in optical in vivo imaging, there is an increasing demand of photostable near-infrared (NIR) dyes. Herein we report the rational design of an amine tricarbocyanine structure with improved photostability (CyNA) and its combinatorial derivatization to render CyNA-414 as a NIR-fluorescent dye with stronger emission intensity and higher photostability than the NIR standard IndoCyanine Green (ICG).

Details

Language :
English
ISSN :
1364-548X
Volume :
46
Issue :
39
Database :
MEDLINE
Journal :
Chemical communications (Cambridge, England)
Publication Type :
Academic Journal
Accession number :
20830356
Full Text :
https://doi.org/10.1039/c0cc02366c