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Restoration of nasal cytology after endoscopic turbinoplasty versus laser-assisted turbinoplasty.
- Source :
-
American journal of rhinology & allergy [Am J Rhinol Allergy] 2010 Jul-Aug; Vol. 24 (4), pp. 310-4. - Publication Year :
- 2010
-
Abstract
- Background: Insult from surgical trauma leads to a degeneration of the nasal epithelium, resulting in morphological-volumetric changes involving the entire cell or a specific cell component. Alterations in normal nasal mucosa were assessed by nasal cytology and other functional tests after either endoscopic turbinoplasty or laser-assisted turbinoplasty for reducing inferior turbinate enlargement.<br />Methods: A total of 150 patients with chronic nasal obstruction due to inferior turbinate hypertrophy were randomly assigned to undergo laser-assisted turbinoplasty or endoscopic turbinoplasty. Preoperative and postoperative assessment at 1 and 3 months follow-up included active anterior rhinomanometry, measurement of mucociliary transport time (MCTt), and nasal cytology to determine whether improved nasal breathing was accompanied by a restoration of preoperative nasal cytology and MCTt. One year after the operation, nasal cytology was repeated to definitively evaluate the presence of surgery-related cytological damage.<br />Results: At both postoperative visits, nasal resistance had decreased similarly in both treatment groups; mean MCTt was significantly shorter in the endoscopic turbinoplasty-treated group (p < 0.05); at both visits, the number of altered ciliated cells had increased in the laser-assisted turbinoplasty-treated group but decreased in the endoscopic turbinoplasty-treated group, which, unlike the laser-assisted turbinoplasty-treated group, was also noted to have progressed toward a significant improvement in the goblet-to-ciliated cell ratio (p < 0.01).<br />Conclusion: When compared with laser-assisted turbinoplasty, endoscopic turbinoplasty is a conservative technique for inferior turbinate reduction that allows better restoration of preoperative nasal cytology and shorter MCTt.
- Subjects :
- Adult
Aged
Breath Tests
Cell Death
Female
Follow-Up Studies
Goblet Cells pathology
Humans
Hypertrophy diagnosis
Hypertrophy pathology
Male
Middle Aged
Mucociliary Clearance
Nasal Mucosa injuries
Nasal Mucosa surgery
Rhinomanometry
Surgical Wound Dehiscence prevention & control
Turbinates pathology
Endoscopy adverse effects
Hypertrophy therapy
Laser Therapy adverse effects
Nasal Mucosa pathology
Surgical Wound Dehiscence etiology
Turbinates surgery
Subjects
Details
- Language :
- English
- ISSN :
- 1945-8932
- Volume :
- 24
- Issue :
- 4
- Database :
- MEDLINE
- Journal :
- American journal of rhinology & allergy
- Publication Type :
- Academic Journal
- Accession number :
- 20819472
- Full Text :
- https://doi.org/10.2500/ajra.2010.24.3474