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[The competitive relations of tamoxifen and estradiol at the level of the plasma membranes of the target cells].

Authors :
Mineeva EN
Source :
Farmakologiia i toksikologiia [Farmakol Toksikol] 1990 Nov-Dec; Vol. 53 (6), pp. 26-7.
Publication Year :
1990

Abstract

The specific binding of an antiestrogen tamoxifen to receptors of estradiol of target cells plasmic membranes of the human endometrium was studied in some hyperplastic processes. The relative binding activity of tamoxifen was determined. Tamoxifen was found to compete with estradiol for binding to plasmic membranes of the endometrial cells.

Details

Language :
Russian
ISSN :
0014-8318
Volume :
53
Issue :
6
Database :
MEDLINE
Journal :
Farmakologiia i toksikologiia
Publication Type :
Academic Journal
Accession number :
2081562