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[Quality control and discrimination of angelica different processed products based on HPLC fingerprints combined chemometrics methods].

Authors :
Guo Y
Hua Y
Du T
Yang H
Wei Y
Source :
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica [Zhongguo Zhong Yao Za Zhi] 2010 Jun; Vol. 35 (12), pp. 1551-5.
Publication Year :
2010

Abstract

Objective: To establish a chemical fingerprint method for reorganizing and validating angelica different processed products.<br />Method: A high-performance liquid chromatographic method was developed to establish the fingerprint. Principal component analysis, hierarchical cluster analysis and discriminate analysis were applied to study HPLC finger printing and chemical pattern reorganization.<br />Result: There were difference of characteristic peaks and its relative peak area of HPLC fingerprints between different processed products. Fish's discriminate functions were generated by using six selected predictor variables, the tested samples of different processed products were classified with 100% accuracy, and discriminate analysis plots for the five groups were well-resolved.<br />Conclusion: The developed HPLC finger print, combined with chemometrics, can accurately identify and validate angelica different processed products, the research provide theoretical basis for the processing mechanism and quality assess of angelica different processed products.

Details

Language :
Chinese
ISSN :
1001-5302
Volume :
35
Issue :
12
Database :
MEDLINE
Journal :
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica
Publication Type :
Academic Journal
Accession number :
20815205
Full Text :
https://doi.org/10.4268/cjcmm20101210