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Progression of low back and lower extremity pain in a cohort of patients with achondroplasia.
- Source :
-
Journal of neurosurgery. Spine [J Neurosurg Spine] 2010 Sep; Vol. 13 (3), pp. 335-40. - Publication Year :
- 2010
-
Abstract
- Object: The aim of this study was to assess the natural history of pain associated with spinal stenosis in individuals with achondroplasia and to characterize pain patterns and associated functional and psychological effects.<br />Methods: The authors measured pain severity, spatial distribution of pain, functional disability, psychological distress, physical symptoms other than pain, and healthcare utilization in 181 individuals with achondroplasia. They also assessed low back and/or lower extremity pain at the initial visit and 1-year follow-up via self-rated patient questionnaires, calculated composite scores from responses via component analyses, and used repeated measures linear regression analyses for score changes (significance, p < or = 0.05).<br />Results: At the follow-up, back pain severity was unchanged. Patients reported significant progression of pain toward involvement of the lower extremities and significant increases in lower extremity pain severity overall. There were also significant increases in healthcare utilization overall. Compared with patients with back pain only, those with back pain and proximal or distal leg pain had higher self-rated pain severity; higher functional disability; and more bowel and bladder dysfunction symptoms, sleep disturbances, extremity numbness, and psychological distress.<br />Conclusions: Individuals with achondroplasia and symptomatic spinal stenosis often experience back pain, which may progress to lower extremity pain and debilitating consequences. A more thorough understanding of the progression of spatial pain characteristics and pain severity may aid clinical decision making regarding the optimal timing for intervention.
- Subjects :
- Achondroplasia complications
Achondroplasia psychology
Adolescent
Adult
Aged
Cohort Studies
Disability Evaluation
Disease Progression
Female
Follow-Up Studies
Humans
Linear Models
Low Back Pain complications
Low Back Pain psychology
Male
Middle Aged
Pain complications
Pain psychology
Patient Acceptance of Health Care
Severity of Illness Index
Spinal Stenosis complications
Spinal Stenosis physiopathology
Spinal Stenosis psychology
Surveys and Questionnaires
Young Adult
Achondroplasia physiopathology
Leg
Low Back Pain physiopathology
Pain physiopathology
Subjects
Details
- Language :
- English
- ISSN :
- 1547-5646
- Volume :
- 13
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- Journal of neurosurgery. Spine
- Publication Type :
- Academic Journal
- Accession number :
- 20809726
- Full Text :
- https://doi.org/10.3171/2010.3.SPINE09629