[Annular elastolytic giant-cell granuloma].

Authors :: Le Corre Y
Steff M
Prophette B
Celerier P
Maillard H
Source :: Annales de dermatologie et de venereologie [Ann Dermatol Venereol] 2010 Aug-Sep; Vol. 137 (8-9), pp. 532-5. Date of Electronic Publication: 2009 May 28.
Publication Year :: 2010
Abstract: Background: Annular elastolytic giant-cell granuloma (AEGCG) is a rare form of granulomatous dermatosis characterized by annular plaques with central atrophy and raised erythematous margins and is usually located on the facial and neck areas. It is characterized histologically by loss of elastic fibre and elastophagocytosis. We report a case of AEGCG.<br />Case Report: A 72-year-old man consulted for annular plaques, some of which were atrophic, and papules that had been present for 2 years. The lesions involved sun-exposed and non-sun-exposed skin. The biopsies showed granulomatous infiltrates and discrete elastophagocytosis. After ruling out various differential clinical and histological diagnoses, the patient was diagnosed with AEGCG.<br />Discussion: We report a case of AEGCG. Diagnosis was not easy. The differential diagnoses of this entity were discussed and we ruled out actinic granuloma, sarcoidosis, leprosy, and granuloma annulare. Our patient presented the classical annular variant combined with a papular variant. We report the first case involving response to isotretinoin.<br /> (Copyright 2009 Elsevier Masson SAS. All rights reserved.)