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The feasibility of in vivo detection of gadolinium by prompt gamma neutron activation analysis following gadolinium-based contrast-enhanced MRI.
- Source :
-
Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine [Appl Radiat Isot] 2011 Jan; Vol. 69 (1), pp. 105-11. Date of Electronic Publication: 2010 Aug 05. - Publication Year :
- 2011
-
Abstract
- The feasibility of using the McMaster University in vivo prompt gamma neutron activation analysis system for the detection of gadolinium has been investigated. Phantoms have been developed for the kidney, liver, and the leg muscle. The initial detection limits are determined to be 7.2 ± 0.3 ppm for the kidney, 3.0 ± 0.1 ppm for the liver, and 2.33 ± 0.08 ppm for the lower leg muscle. A few system optimizations have been tested and show significant detection limit reduction from these initial values. The technique is promising and shows feasibility for in vivo studies of gadolinium retention.<br /> (Copyright © 2010 Elsevier Ltd. All rights reserved.)
Details
- Language :
- English
- ISSN :
- 1872-9800
- Volume :
- 69
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine
- Publication Type :
- Academic Journal
- Accession number :
- 20727776
- Full Text :
- https://doi.org/10.1016/j.apradiso.2010.07.023