Back to Search
Start Over
In combined first-trimester Down syndrome screening, the false-positive rate is not higher in pregnancies conceived after assisted reproduction compared with spontaneous pregnancies.
- Source :
-
Fertility and sterility [Fertil Steril] 2011 Jan; Vol. 95 (1), pp. 378-81. Date of Electronic Publication: 2010 Aug 19. - Publication Year :
- 2011
-
Abstract
- The maternal serum levels of pregnancy-associated plasma protein-A (PAPP-A) were reduced in hormonally stimulated pregnancies in the in vitro fertilization and intracytoplasmic sperm injection groups (N=176; PAPP-A: 0.82) and in the entire assisted reproduction group (N=282; PAPP-A: 0.83) as compared with controls (N=24,783; PAPP-A: 0.94). However, the false-positive rate of first-trimester combined screenings was not statistically significantly increased in assisted reproduction pregnancies after adjustment for maternal age.<br /> (Copyright © 2011 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.)
- Subjects :
- Adolescent
Adult
Chorionic Gonadotropin, beta Subunit, Human blood
False Positive Reactions
Female
Humans
Mass Screening statistics & numerical data
Maternal Age
Middle Aged
Pregnancy
Pregnancy-Associated Plasma Protein-A metabolism
Risk Factors
Young Adult
Biomarkers blood
Down Syndrome blood
Down Syndrome diagnosis
Down Syndrome epidemiology
Pregnancy Trimester, First blood
Prenatal Diagnosis statistics & numerical data
Reproductive Techniques, Assisted statistics & numerical data
Subjects
Details
- Language :
- English
- ISSN :
- 1556-5653
- Volume :
- 95
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Fertility and sterility
- Publication Type :
- Academic Journal
- Accession number :
- 20723891
- Full Text :
- https://doi.org/10.1016/j.fertnstert.2010.07.1048