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Comparison of isolates of Mycoplasma mycoides subspecies capri from asymptomatic and septicaemic goats.
Comparison of isolates of Mycoplasma mycoides subspecies capri from asymptomatic and septicaemic goats.
- Source :
-
Journal of comparative pathology [J Comp Pathol] 2011 Jan; Vol. 144 (1), pp. 70-7. Date of Electronic Publication: 2010 Aug 12. - Publication Year :
- 2011
-
Abstract
- Strains of Mycoplasma mycoides subspecies capri (Mmc) are frequently isolated from goats with contagious agalactia, but they can also be recovered from herds that have shown no clinical signs of mycoplasmosis for several years. The present study was conducted in order to explore the potential genetic and antigenic differences existing between an Mmc strain isolated from an outbreak (septicaemic) and a strain isolated from the ear canal of a goat belonging to a herd with no recent episode of mycoplasmosis (carriage strain). The genomes of the two strains, compared by suppression subtractive hybridization, were shown to be poorly divergent. The two strains were inoculated into goats to produce specific antisera, but both induced fatal mycoplasmosis. These results indicate that septicaemic and carriage strains cannot be distinguished by their genetic background or by their pathogenic capacity under experimental conditions.<br /> (Copyright © 2010 Elsevier Ltd. All rights reserved.)
- Subjects :
- Animals
Genomics
Goat Diseases pathology
Goat Diseases transmission
Goats
Mycoplasma mycoides genetics
Mycoplasma mycoides immunology
Nucleic Acid Hybridization methods
Pleuropneumonia, Contagious pathology
Pleuropneumonia, Contagious transmission
Sepsis microbiology
Sepsis pathology
Sequence Analysis, DNA
Species Specificity
Goat Diseases microbiology
Mycoplasma mycoides isolation & purification
Pleuropneumonia, Contagious microbiology
Sepsis veterinary
Subjects
Details
- Language :
- English
- ISSN :
- 1532-3129
- Volume :
- 144
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Journal of comparative pathology
- Publication Type :
- Academic Journal
- Accession number :
- 20708197
- Full Text :
- https://doi.org/10.1016/j.jcpa.2010.06.004