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[Biotransformation of the anticholinesterase agent, 9-amino-7-methoxy-1,2,3,4-tetrahydroacridine].
- Source :
-
Ceskoslovenska farmacie [Cesk Farm] 1991 May; Vol. 40 (3), pp. 130-2. - Publication Year :
- 1991
-
Abstract
- Biotransformation of the anticholinesterasic agent 9-amino-7-methoxy-1,2,3,4-tetrahydroacridine was studied in the laboratory rat. In the animal urine, the main identified metabolites were 9-amino-7-hydroxy-1,2,3,4-tetrahydroacridine and its conjugate with glucuronic acid, or sulfuric acid, as well as 9-amino-1-hydroxy-7-methoxy-1,2,3,4-tetrahydroacridine and 9-amino-2-hydroxy-7-methoxy-1,2,3,4-tetrahydroacridine. A part of the drug was excreted in an unchanged form.
Details
- Language :
- Czech
- ISSN :
- 0009-0530
- Volume :
- 40
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- Ceskoslovenska farmacie
- Publication Type :
- Academic Journal
- Accession number :
- 2070431