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Pulmonary manifestations of systemic lupus erythematosus.
- Source :
-
Clinics in chest medicine [Clin Chest Med] 2010 Sep; Vol. 31 (3), pp. 479-88. - Publication Year :
- 2010
-
Abstract
- Systemic lupus erythematosus (SLE) is a potentially severe, frequently disabling autoimmune disease with multiorgan involvement and a typically waxing and waning course. SLE is often considered the prototypical autoimmune disease. Although SLE has the potential to affect any organ, the lungs are commonly involved later in the course of the disease in the setting of other organ involvement. Pulmonary disease may complicate SLE and is an important cause of morbidity and mortality. The most common pulmonary manifestation attributable to SLE is pleuritis, but other pleural involvement can be seen, as well as parenchymal disease, pulmonary vascular disease, diaphragmatic dysfunction, and upper airway dysfunction. Finding the true prevalence of lung involvement with SLE is complicated by the high rates of pulmonary infections. This article reviews the diverse clinical symptoms and immunologic pulmonary manifestations of SLE.
- Subjects :
- Bronchial Diseases diagnosis
Bronchial Diseases etiology
Humans
Lung Diseases diagnosis
Lung Diseases therapy
Pleural Diseases diagnosis
Pleural Diseases therapy
Respiratory Tract Infections complications
Lung Diseases etiology
Lupus Erythematosus, Systemic complications
Pleural Diseases etiology
Subjects
Details
- Language :
- English
- ISSN :
- 1557-8216
- Volume :
- 31
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- Clinics in chest medicine
- Publication Type :
- Academic Journal
- Accession number :
- 20692540
- Full Text :
- https://doi.org/10.1016/j.ccm.2010.05.001